United Kingdom

Findings from the latest published COVID-19 REACT-1 study

  • As part of the world’s most important COVID-19 study, more than 140,000 volunteers were tested in the United Kingdom between March 11-30, 2021.
  • According to a study by Imperial College London and Ipsosmori, infections have decreased by about 60% since the last REACT study in February, with only 1 in 500 infected.
  • The data suggest that the infection has led to a decrease in mortality since December. This is consistent with the deployment of vaccinations during this period and the rules of the “Stay-at-home order”.
  • The epidemic is now flat, demonstrating that it is important for everyone to continue to follow the guidance and rules to help control the epidemic.

Between March 11th and 30th, more than 140,000 volunteers in the United Kingdom underwent PCR testing to determine the level of infection in the general population. According to the latest data, infections in the UK have decreased by about 60% since the last REACT report published on March 4th (covering the period from February 4th to 23rd). Compared to the February survey results, a sharp drop in prevalence was seen in London and the southeast.

Studies show that the rate of decline begins to level off in mid-March, requiring everyone to continue to follow the rules as they progress along the roadmap, remembering to follow guidance on hands, face, space and fresh air. It is increasing.

The study also found that the correlation between prevalence of infectious diseases and mortality is currently diverging, and that infectious diseases have led to a reduction in deaths since the start of widespread vaccination by government vaccination programs. It suggests that it may have been.

The main findings from the 10th round of the REACT study show:

  • In the latest round of March, the survey estimated the UK’s R number to be 1.
  • Between February and March, the national prevalence fell by about 60% from 0.49% in February to 0.20% in March.
  • From February to March, the prevalence of the area dropped significantly. In the southeast, it decreased from 0.36% in February to 0.07% in March. London is 0.60% to 0.16%. East England 0.47% to 0.15%; East of England 0.59% to 0.19%. Northwest is 0.69% to 0.31%
  • In part of the northwest, Yorkshire and the Humber, areas with high prevalence remain.
  • The highest prevalence in March was 0.41% for ages 5-12, while the prevalence for ages 65-74 and over 75 was the lowest at 0.09%.
  • Infectious diseases may have reduced hospitalization and mortality since the start of widespread vaccination

Vaccine programs continue to expand to protect as many people as possible, with more than 37 million doses nationwide to date. Vaccination programs have already had a significant impact on hospitalization and mortality, with prevalence currently lowest at age 75 and older.

Professor Paul Elliott, director of the Imperials School of Public Health REACT program, said:

Since the last survey in February, infectious diseases have decreased by about 60% overall, showing a satisfactory decrease. This is very encouraging and shows that we are heading in the right direction.

However, according to the latest data, the infection rate is flat and the R number is about 1. This shows that we need to continue to be cautious and adhere to the rules.

Kelly Beaver, Managing Director of Public Relations at Ipsos MORI, said:

Currently, more than 1.5 million people in the UK are participating in the REACT study, and the data for this round are very promising, with a 60% reduction in prevalence from the previous round in March.

However, you must be vigilant as you move out of the blockade and advance your roadmap. A R number of 1 means that you need to pay attention to your approach over the next few weeks to months.

Careful relaxation of restrictions is expected to increase infection rates, and it is clear that if the roadmap moves too fast or too fast, there is a risk of unsustainable pressure on the NHS.

The roadmap relies on four tests: successful continuation of the vaccination program, evidence that vaccines are effective in reducing hospitalizations and mortality, infection rates to surge in hospitalizations and NHS No risk of pressure, and no significant new variants of concern Impact on risk assessment. Continued careful relaxation of restrictions based on data rather than vaccination programs, tests, and dates is expected to reduce pressure on the NHS and reduce deaths and hospitalizations.

As part of the first phase of the roadmap, the school was reopened on March 8. This is essential for the education and well-being of children. Earlier this week, the government announced that the second phase of the roadmap would continue as planned on April 12, with outdoor hospitality, non-essential retailers and beauty salons reopening.

The government also announced that everyone in the UK will have access to the twice-weekly high-speed cross-flow test as part of its universal test deployment. It catches asymptomatic cases, prevents people from unknowingly transmitting the virus, and can save lives when restrictions begin to be relaxed.

This report is the latest in a REACT study commissioned by the Ministry of Health and conducted by a world-class team of scientists, clinicians and researchers at Imperial College London, Imperial College Healthcare NHS Trust, and Ipsosmori.

Strong mass surveillance studies are essential to understand the impact of COVID-19 infection rates, how the virus is spreading nationwide, and the measures taken to contain the virus to inform current and future behavior. is.

Background information

Preprint report Downloadable..

For more information Real-time assessment of community infections (REACT) Work program.

This study falls under the fourth pillar of the COVID-19 National Trial Program, which focuses on mass surveillance of the general population.

For more information Rapid inspection..

Findings from the latest published COVID-19 REACT-1 study

SourceFindings from the latest published COVID-19 REACT-1 study

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