Demand for Monkeypox Vaccine Increases as US and European Virus Cases Rise

“This is basically the largest group of chickenpox cases that occur simultaneously outside the endemic region in many countries,” said Boguma Kabisen Titanji, a Cameroonian physician at Emory University in Atlanta.

Bavarian Nordic, manufacturer of the chickenpox vaccine Jynneos is approved by the Food and Drug AdministrationTold POLITICO that he had received calls from “many, many countries” wishing to purchase his staff.

“We’re talking about a lot of countries sending us procurement requests because the problem is getting bigger and bigger,” said Rolf Sass Sorensen, the company’s vice president of investor relations and communications.

The Bavarian Nordic is confident of being able to supply the required doses – unless immediate and acute demand increases. “Of course, we do not have supplies available for the whole planet, but only in the medium and long term will we have quite large opportunities to produce vaccines,” he said.

That’s about 50 million doses a year, Sorensen said. He said the vaccines last for at least three years.

Health officials have confirmed more than 250 cases in 16 countries, most of them in Europe. Most cases of the virus have been reported in the UK, Spain and Portugal, usually causing fever, rash, and lymph nodes. In the United States, the Centers for Disease Control and Prevention said Monday it has confirmed one case of monkey pox in Massachusetts and is considering four cases from New York, Utah and Florida that suggest the monkey is a flower. On Tuesday, California said it was working with the agency to investigate an additional suspicious case.

Cases of monkeys outside the endemic region are very rare, usually bringing people from this area to non-endemic countries. Last year, for example, the U.S. had two cases of the monkey flower being imported by travelers who were in Nigeria, according to the CDC.

While routine vaccination against chickenpox was still practiced globally, chickenpox was not detected because the vaccine protected against both diseases. Since chickenpox has been global Eliminated in 1980 And those vaccinations stopped, a monkey flower appeared, health officials say.

“We have a strong concern that the virus is spreading differently,” Jennifer McQuiston, deputy director of the CDC’s High Outcome Pathogens and Pathology Division, told reporters at a briefing Monday.

U.S. health officials say the country has a “good supply” of vaccines against the monkey flower. But the current containment strategy, which includes vaccinating high-risk, close contacts with infected patients, could quickly strain the current supply of Jynneos if cases increase.

“This is one of the few diseases that can be vaccinated after exposure, and it prevents you from getting sick,” said Eric Toner, a senior fellow at the Johns Hopkins School of Public Health in Bloomberg.

The U.S. National Strategic Reserve has more than 1,000 doses of Jynneos approved by the FDA in 2019, as well as 100 million doses of the old chickenpox vaccine, which has more side effects, according to the CDC.

“We expect this level to rise very rapidly in the coming weeks as the company delivers more doses,” McQuiston said of the Jynneos vaccine. He said the agency had already requested part of these doses for patient contacts.

The UK has already started vaccinating people, 1000 doses of a vaccine called Imvanex has already been introduced. The country was left with 3,500 doses. Germany ordered 40,000 doses, The information is spread by Reuters.

two FDA approved antivirus products Chickenpox can also be used to treat chickenpox, Brett Petersen, medical officer at the CDC High Outcome Pathology and Pathology Unit, told reporters Monday.

One of the drugs, Tecovirimat, is already in national stock, and the CDC is now developing treatment guidelines to assist public health agencies and clinics in administering it as needed, he said.

Tecovirimate is also approved for the treatment of monkeys in Europe. SIGA, a spokesman for its manufacturer, said the company could not comment on orders.

The U.S. government is in talks with a second drug manufacturer, Brincidofovir, to purchase doses for supplies and provide immediate access to the drug used to treat monkeys.

Vaccines and drugs are not widely available commercially because they are relatively new, said Rosamund Lewis, head of the World Health Organization’s Chickenpox Secretariat. The World Health Organization will work with industry on “what we can do now to improve access to these products,” he told a public information session on Monday.

Nevertheless, the monkey flower is not as contagious as Covid-19 and it is expected that it will not cause millions of infections and deaths as Covid did.

“Of all the things in the world today that people need to worry about, this is probably not one of them,” Toner said.

The Biden administration has struggled in recent days to characterize how concerned Americans should be about the epidemic, wanting to raise awareness of a disease that most people are unaware of but hate to cause new panic in a country plagued by pandemics.

On Sunday, President Joe Biden said monkey pox was “something that everyone should be concerned about,” only to soften his message the next day, saying he did not pose the same risk as Covid-19.

The virus is usually transmitted to humans through direct contact with infected animals, usually in highland areas. Eleven African countries – including Cameroon, the Democratic Republic of the Congo and Nigeria. In the last six months, four endemic countries have been reported 1300 cases and about 60 killed.

The virus is also transmitted between humans through skin lesions or close contact with recently contaminated objects.

Numerous cases reported outside of endemic countries appear to have been spread through sexual contact and other close contact Super spreading events In Europe. Many, but not all, are among men who have sex with men.

Andy Seale, WHO’s advisor on the Sexually Transmitted Infections Program, has warned against stigmatizing men who have sex with men in the face of an epidemic. “It’s not a gay disease, as some people have tried to label it on social media,” he said. “Anyone can get chickenpox through close contact.”

In African countries where the virus has been routinely detected for the past 50 years, the spread of the epidemic is usually controlled without vaccines and antiviruses, said Cabisen Titanji. This means that the local health authorities isolated the infected people until the symptoms resolved and they followed close contacts, he said. It can take up to four weeks for the infected person to become infected as long as the rash persists, he said.

Belgium has already introduced Mandatory 21-day quarantine For infected people. Close contacts are not required for self-isolation in Belgium, but I recommend the UK they are doing. Biden said Monday that quarantine was not needed in the U.S. because the country has enough doses of the vaccine to fight any serious exacerbations. Reported the Washington Post.

Distribution to Western countries could potentially benefit endemic countries if it increases funding for vaccines and treatments to stop monkey epidemics at source, said Cabisen Titanji.

Demand for Monkeypox Vaccine Increases as US and European Virus Cases Rise

Source link Demand for Monkeypox Vaccine Increases as US and European Virus Cases Rise

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